Lehigh Team Uses Digital Twin of Gut-Brain Axis to Advance Neurostimulation Therapies
A team of researchers at Lehigh University has developed one of the first comprehensive mathematical models of the neural circuitry linking the gut and brain, a “digital twin” designed to simulate how bidirectional signaling regulates stomach function. The work, described in Frontiers in Physiology, could help bioelectronic medicine researchers understand disorders of gut-brain interaction and accelerate the development of neuromodulation therapies such as vagus nerve stimulation.